产品说明
一般描述
Human polo-like kinase 1 (PLK1) is a serine/threonine kinase, that is located on human chromosome 16p12.
免疫原
The antiserum was produced against synthesized peptide derived from human PLK1 around the phosphorylation site of Thr210.
Immunogen Range: 176-225
生化/生理作用
Polo-like kinase 1 (PLK1) plays an important role in the functional maturation of mitotic centrosomes. It actively participates in the development of the cell cycle. This gene is considered as an important therapeutic target as it is overexpressed in several cancer types.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 68 kDa |
| species reactivity | mouse, rat, human |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:1000 immunohistochemistry: 1:50-1:100 |
| NCBI登记号 | P53350 |
| UniProt登记号 | P53350 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PLK1(5347) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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