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Anti-Phospho-PLN-S16/T17 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5701817
包装型号
规格纯度
参考价格
4266.29 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Phospho-PLN-S16/T17 antibody produced in rabbit
产品介绍:

产品说明

一般描述

The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy.

免疫原

A synthetic phosphorylated peptide around of human Phospho-PLN-S16/T17.

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

产品性质

生物来源rabbit
质量水平100
antibody product typeprimary antibodies
克隆polyclonal
形式liquid
species reactivitymouse, human
浓度0.84 mg/mL
technique(s)western blot: 1:500-1:2000
UniProt登记号P26678
运输wet ice
储存温度−20℃
Gene Informationhuman ... PLN(5350)

安全信息

闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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