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Anti-Phospho-Raf1-S259 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5701850
包装型号
规格纯度
参考价格
5406.77 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
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产品名称:
Anti-Phospho-Raf1-S259 antibody produced in rabbit
产品介绍:

产品说明

一般描述

This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]

免疫原

A phospho specific peptide corresponding to residues surrounding S259 of human Phospho-Raf1-S259

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

产品性质

生物来源rabbit
质量水平100
antibody product typeprimary antibodies
克隆monoclonal
形式liquid
species reactivitymouse, human
浓度1.25 mg/mL
technique(s)western blot: 1:500-1:2000
UniProt登记号P04049
运输wet ice
储存温度−20℃
Gene Informationhuman ... RAF1(5894)

安全信息

闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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