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Anti-phospho-Smad2 (pSer250) antibody produced in rabbit

抗 磷酸化 Smad2 (pSer 250 ) 兔抗

品牌
Sigma-Aldrich
货号
SAB4504207
规格纯度
affinity isolated antibody
参考价格
5045.46 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-phospho-Smad2 (pSer250) antibody produced in rabbit
抗 磷酸化 Smad2 (pSer 250 ) 兔抗
产品介绍:

产品说明

一般描述

SMAD2 (SMAD family member 2) is also called as MADR2 (substrate of the TGFβ receptor). It is located on human chromosome 18q21. This gene belongs to the mothers against Dpp (MAD) related family of proteins. SMAD2 has two highly conserved amino and carboxyl-terminal domains (MH1 and MH2 domains) but has no known structural motifs.

免疫原

The antiserum was produced against synthesized peptide derived from human Smad2 around the phosphorylation site of Ser250.

Immunogen Range: 216-265

应用

Anti-phospho-Smad2 (pSer250) antibody has been used in immunoblotting.

生化/生理作用

SMAD2 (SMAD family member 2) plays an important role in TGF-β(transforming growth factor β)/activin signaling pathways. Mutations in SMAD2 (SMAD family member 2) results in arterial aneurysms and dissections. Upregulation of Smad2 blocks the multiplication of gingival epithelial cells. Smad2 positively and negatively controls TGFβ-dependent transcription with the help of forkhead DNA-binding protein FAST2.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 52 kDa
species reactivitymouse, rat, human
浓度~1 mg/mL
technique(s)ELISA: 1:10000
western blot: 1:500-1:1000
NCBI登记号Q15796
UniProt登记号Q15796
application(s)research pathology
运输wet ice
储存温度−20℃
Gene Informationhuman ... SMAD2(4087)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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