Anti-Phospho-TMEM173-S366 antibody produced in rabbit

产品说明

一般描述

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

免疫原

A phospho specific peptide corresponding to residues surrounding S366 of human TMEM173.

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

产品性质

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