产品说明
一般描述
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
免疫原
A synthetic phosphorylated peptide around Y1054 & Y1055 of human Tyk2 (NP_003322.3).
外形
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
产品性质
生物来源 | rabbit |
质量水平 | 100 |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | liquid |
species reactivity | rat, human, mouse |
浓度 | 2.37 mg/mL |
technique(s) | immunohistochemistry: 1:50-1:100 immunohistochemistry: 1:50-1:200 western blot: 1:500-1:2000 |
UniProt登记号 | P29597 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... Tyk2(7297) |
安全信息
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich