Anti-Phospho-VASP-S239 antibody produced in rabbit

产品说明

一般描述

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

免疫原

A phospho specific peptide corresponding to residues surrounding S239 of human Phospho-VASP-S239

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

产品性质

安全信息