产品说明
一般描述
The PIWI-like protein 1 (PIWIL1) belongs to the Piwi subfamily.gene is mapped to human chromosome 12q24.33. It is expressed in the cytosol of spermatocytes and spermatids. PIWI-like protein 1 (PIWIL1) is also an Argonaute protein family member.
特异性
Anti-PIWIL1 recognizes human and mouse PIWIL1.
应用
Anti-PIWIL1 antibody produced in rabbit has been used in western blotting and immunohistochemistry.
生化/生理作用
The PIWI-like protein 1 (PIWIL1) mediates spermatogenesis. Its aberrant expression favors tumor progression inadenocarcinoma. PIWI-like protein 1 (PIWIL1) plays a key role in embryogenesis, differentiation, stem cell proliferation, growth, and development. High levels of PIWIL1 expression is implicated in the colorectal cancer invasion.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
储存及稳定性
Store at –20 ℃. For continuous use, the product may be stored at 2–8 ℃ for up to one month. For extended storage, freeze at –20 ℃ in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~95 kDa |
| species reactivity | mouse, human |
| 包装 | antibody small pack of 25 μL |
| 浓度 | ~1.0 mg/mL |
| technique(s) | immunohistochemistry: 10-20 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded mouse testis and biotin / ExtrAvidinTM-Peroxidase staining system. western blot: 1-2 μg/mL using lysates of HEK-293Tcells over expressing human PIWIL1. |
| UniProt登记号 | Q96J94 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PIWIL1(9271) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
