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Anti-PODXL antibody produced in goat

品牌
Sigma-Aldrich
货号
SAB2500809
规格纯度
affinity isolated antibody, buffered aqueous solution
参考价格
7062.55 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-PODXL antibody produced in goat
Anti-MGC138240
Anti-Gp200
Anti-PCLP
Anti-Podocalyxin-like
产品介绍:

产品说明

一般描述

PODXL (podocalyxin like) is an anti-adhesive transmembrane protein which belongs to the sialomucin protein family. It is associated with cancer development and aggressiveness. The protein is expressed in various cells including epithelial cells of kidney glomeruli, vascular endothelial cells, hematopoietic stem cells and platelets. The gene encoding PODXL is localized on human chromosome 7q32.3.

免疫原

Peptide with sequence C-DNLTKDDLDEEEDTH from the C Terminus of the protein sequence according to NP_001018121.1 ; NP_005388.2.

生化/生理作用

PODXL (podocalyxin like) acts as an anti-adhesion molecule in kidney open filtration pathways. It interacts with the actin-binding protein ezrin in cancer. Using ezrin and the bridging protein NHERF (Na+/H+) exchanger regulatory factor, it connects to the cytoskeleton to regulate cytoskeletal-related functions in tumor progression. In human, PODXL stimulates the cell adherence capacity to immobilized ligands and vascular endothelial cells in presence of integrins.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

质量水平100
生物来源goat
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
species reactivityrat, human, canine, mouse
technique(s)indirect ELISA: suitable
western blot: suitable
UniProt登记号O00592
运输dry ice
储存温度−20℃
Gene Informationhuman ... PODXL(5420)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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