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Anti-PPIB antibody produced in rabbit

品牌
Sigma-Aldrich
货号
HPA012720
规格纯度
Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
参考价格
6389.73 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-PPIB antibody produced in rabbit
Anti-SCYLP
Anti-Rotamase
Anti-S-cyclophilin
Anti-Cyclophilin B
Anti-PPIase
Anti-Peptidyl-prolyl cis-trans isomerase B precursor
Anti-CYP-S1
产品介绍:

产品说明

一般描述

Peptidyl -prolyl cis-trans isomerase B (PPIB) is a cyclosporin A binding protein localized to the calcium-containing intracellular vesicles. It is expressed in the endoplasmic reticulum and nuclear matrix. The gene encoding this protein is present on chromosome 15.

免疫原

Peptidyl-prolyl cis-trans isomerase B precursor recombinant protein epitope signature tag (PrEST)

应用

Anti-PPIB antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting.† To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Western Blotting (1 paper)

生化/生理作用

Peptidyl -prolyl cis-trans isomerase B (PPIB) is involved in the activation of peripheral blood T-lymphocytes and has the ability to mediate immunosuppressant Cyclosporin A inhibition. It interacts with growth hormone and prolactin, and acts as a chaperone facilitating their nuclear retro-transport. Mutations in the gene cause severe osteogenesis imperfecta.

特点和优势

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:

  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.

联系

Corresponding Antigen APREST72173.

外形

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide

法律信息

Prestige Antibodies is a registered trademark of sigma-aldrich Co. LLC

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

人类蛋白质图谱编号HPA012720    Human Protein Atlas characterization data

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
产品线Prestige Antibodies® Powered by Atlas Antibodies
形式buffered aqueous glycerol solution
species reactivityrat, human, mouse
包装antibody small pack of 25 μL
增强验证orthogonal RNAseq
RNAi knockdown
Learn more about Antibody Enhanced Validation
technique(s)immunoblotting: 0.04-0.4 μg/mL
immunofluorescence: 0.25-2 μg/mL
immunohistochemistry: 1:500-1:1000
免疫原序列LKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIEVEKPFAIAKE
UniProt登记号P23284
运输wet ice
储存温度−20℃
Gene Informationhuman ... PPIB(5479)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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