Anti-PPID Antibody, clone 6A5.1

产品说明

一般描述

PPIase D is one of a family peptidyl-prolyl-isomerases that help proteins fold during synthesis. Specifically, PPIases D catalyzes the cis-trans isomerization of proline imidic peptide bonds in peptides. Among the proteins assisted by PPIase D are HSP90, Estrogen receptor, cellular dynein, MYB, ILF2, XRCC6, GNB2L1 and RPS3. PPIase D also may regulate the interactions of other proteins including MYB and AHR. Through its protein folding exercise PPIase D becomes vital for proper protein transport and expression as well. Finally PPIase D is associated with assisting in the response to UV light induced apoptosis, cell viability in anaplastic lymphoma and hepatitis C virus replication and release. PPIase can be found localized in both the cytoplasm and the nucleus and is widely expressed. Note PPIase should not be confused with PPIF, or mitochondrial peptidyl-prolyl cis-trans isomerase F.

免疫原

Recombinant protein corresponding to human PPID.

应用

Research Category
Neuroscience
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected PPID in rat cerebellum tissue.
Research Sub Category
Developmental Signaling
This Anti-PPID Antibody, clone 6A5.1 is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of PPID.

质量

Evaluated by Western Blotting in HepG2 cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected PPID in 10 µg of HepG2 cell lysate.

目标描述

~ 42 kDa observed

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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