产品说明
免疫原
Peptide sequence around aa. 674-678 (R-L-S-F-A), according to the protein PRKCQ.
特点和优势
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目标描述
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. Ref.8 PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | ~80 kDa |
species reactivity | human |
浓度 | 1 mg/mL |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 indirect immunofluorescence: 1:100-1:200 western blot: 1:500-1:1000 |
同位素/亚型 | IgG |
免疫原序列 | (R-L-S-F-A) |
NCBI登记号 | NP_006248.1 |
UniProt登记号 | Q04759 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... PRKCQ(5588) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich