产品说明
免疫原
Peptide sequence around aa. 2607-2611 (V-E-T-Q-A), according to the protein PRKDC.
特点和优势
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目标描述
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
基本信息
MDL编号 | MFCD01321942 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | ~450 kDa |
species reactivity | human |
浓度 | 1 mg/mL |
technique(s) | western blot: 1:500-1:1000 |
同位素/亚型 | IgG |
免疫原序列 | (V-E-T-Q-A) |
NCBI登记号 | NP_001075109.1 |
UniProt登记号 | P78527 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... PRKDC(5591) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich