产品说明
一般描述
Prohibitin is an inhibitor of DNA synthesis that is widely expressed across various tissues. Prohibitin influences proliferation, and may also have a role in regulating mitochondrial respiration activity and in aging. Expression levels of prohibitin in fibroblasts have been found to decrease heterogeneously as cellular aging occurs.
免疫原
KLH-conjugated linear peptide corresponding to human Prohibitin-1 (PHB1).
应用
Anti-Prohibitin-1 (PHB1), clone 1G5C1 | MABC965 is an antibody against Prohibitin-1 for use in Western Blotting, Immunohistochemistry.
Research Sub Category
Apoptosis - Additional
Research Category
Apoptosis & Cancer
Western Blotting Analysis: 1.0 µg/mL from a representative lot detected Prohibitin-1 (PHB1) in 10 µg of NIH/3T3 and HeLa cell lysate.
Immunohistochemistry Analysis: A representative lot detected Prohibitin-1 (PHB1) in rat liver tissue (Kakehashi, A., et al. (2011). Toxicological Sciences. 119(1):61-72).
质量
Evaluated by Western Blotting in rat liver tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected Prohibitin-1 (PHB1) in 10 µg of rat liver tissue lysate.
目标描述
~30 kDa observed
外形
Format: Purified
Purified rat monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
其他说明
Concentration: Please refer to lot specific datasheet.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | rat |
抗体形式 | purified antibody |
antibody product type | primary antibodies |
克隆 | 1G5C1, monoclonal |
species reactivity | mouse, human, rat |
technique(s) | immunohistochemistry: suitable western blot: suitable |
同位素/亚型 | IgG2bκ |
NCBI登记号 | NP_001268425 |
UniProt登记号 | P35232 |
运输 | wet ice |
Gene Information | human ... PHB(5245) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich