Anti-QKI-5 Antibody, clone N195A/16

产品说明

一般描述

QKI (Quaking) is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability, and protein translation. It is regulated by alternative splicing. There are at least 6 known isoforms, and QKI-5 refers to isoforms 1, which is the ′canonical′ sequence, consisting of 341 amino acids.

特异性

This antibody does not cross react with QKI-6, QKI-7, and QKI-7b. This antibody may cross react with other STAR proteins containing similar nuclear localization signals (Prof. J. Trimmer, Univerisity of California, Davis.).

免疫原

Linear peptide corresponding to human QKI-5.

应用

Detect QKI using this mouse monoclonal antibody, Anti-QKI-5 Antibody, clone N195A/16 validated for use in IHC & western blotting.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected QKI-5 in human cerebellum and thalamus tissues, and in rat hippocampus tissue.

Western Blotting Analysis: A representative lot detected QKI-5 in COS cell lysates transiently transfected with Flag-tagged QKI-5 (Prof. J. Trimmer, University of California, Davis.).

质量

Evaluated by Immunohistochemistry in rat cerebellum tissue.

Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected QKI-5 in rat cerebellum tissue.

目标描述

45 kDa calculated

外形

Protein G Purified
Format: Purified

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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