产品说明
一般描述
Ras-related protein Rab-11A (RAB11A), member RAS oncogene family, is a GTP binding protein. RAB11A gene is located on human chromosome 15q21.3. RAB11A is expressed abundantly in tissues with high secretion.
免疫原
RAB11A (NP_004654.1, 1 a.a. ~ 216 a.a) full-length human protein.
Sequence
MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSDRRENDMSPSNNVVPIHVPPTTENKPKVQCCQNI
生化/生理作用
Ras-related protein Rab-11A (RAB11A), member RAS oncogene family, is involved in vesicle trafficking during recycling of endosomes. Overexpression of RAB11A leads to an increased collective cell invasion in colorectal carcinoma.RAB11A and its binding partners plays a crucial role in recycling of human β1-adrenergic receptor.
外形
Solution in phosphate buffered saline, pH 7.4
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~24.4 kDa |
| species reactivity | human |
| technique(s) | western blot: 1 μg/mL |
| NCBI登记号 | NM_004663 |
| UniProt登记号 | P62491 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... RAB11A(8766) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
