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Anti-RAD21 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4502562
规格纯度
affinity isolated antibody
参考价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-RAD21 antibody produced in rabbit
NXP-1
SCC1 homolog
Double-strand-break repair protein rad21 homolog
Nuclear matrix protein 1
hHR21
产品介绍:

产品说明

一般描述

Anti-RAD21 Antibody detects endogenous levels of total RAD21 protein.
RAD21 (RAD21 homolog, S. pombe) is a novel nuclear protein located on chromosome 8q24.

免疫原

The antiserum was produced against synthesized peptide derived from human RAD21.

Immunogen Range: 521-570

应用

Anti-RAD21, C-Terminal antibody produced in rabbit is suitable for indirect ELISA and western blot applications.

生化/生理作用

RAD21 (RAD21 homolog, S. pombe) plays a crucial role in normal cell division. It acts as a main component of the cohesin complex for the proper chromosomal arrangement during cell division. The protein possesses two mitotic cleavage sites for the attachment of separase. It has been shown experimentally that at the beginning of anaphase stage, a caspase-like Esp1/separase attaches to the cleavage site of RAD21 and initiate sister chromatid separation, which is an essential step for the completion of cytokinesis. During double strand DNA damage repair, it helps the two DNA strands to adhere with each other. Mutation in RAD21 causes a congenital phenotype, cohesinopathy in humans characterized with growth retardation and minor skeletal anomalies.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 71 kDa
species reactivitymouse, human
浓度~1 mg/mL
technique(s)ELISA: 1:1000
western blot: 1:500-1:1000
NCBI登记号O60216
UniProt登记号O60216
运输wet ice
储存温度−20℃
Gene Informationhuman ... RAD21(5885)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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