产品说明
一般描述
The role of the protein retinol binding protein 4 (RBP4) has always been understood to be involvement in the transport of vitamin A. However, research has demonstrated that blood levels of RBP4 is closely linked with the development of insulin resistance, which predisposes individuals to type 2 diabetes and is a major risk factor for cardiovascular disease. In addition higher levels of RBP4 were closely associated with other components of metabolic syndrome, including increased body mass index, waist-to-hip ratio, serum triglyceride levels and systolic blood pressure, as well as decreased HDL levels. Further investigations indicate that RBP4 may be a useful biomarker in identifying a predisposition to type 2 diabetes and measuring therapeutic improvement.
免疫原
Recombinant protein corresponding to human RBP4.
应用
Research Sub Category
Metabolic Hormones & Receptors
Anti-RBP4 Antibody is a highly specific rabbit polyclonal antibody, that targets Retinol binding protein 4 & has been tested in western blotting.
Western Blotting Analysis: 2.0 µg/mL from a representative lot detected RBP4 in 10 µg of human spleen, thymus, ovary and testis tissue lysates.
Research Category
Signaling
质量
Evaluated by Western Blotting in human liver tissue lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected RBP4 in 10 µg of human liver tissue lysate.
目标描述
~23 kDa observed
联系
Replaces: MABN1095
外形
Affinity purified
Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human |
technique(s) | western blot: suitable |
NCBI登记号 | NP_006735 |
UniProt登记号 | P02753 |
运输 | wet ice |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich