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位置:首页 > 品牌 > Sigma-Aldrich > Anti-Retinal Dehydrogenase 1/ALDH1A1 Antibody, clone 8D7.1

Anti-Retinal Dehydrogenase 1/ALDH1A1 Antibody, clone 8D7.1

品牌
Sigma-Aldrich
货号
MABN838
规格纯度
clone 8D7.1, from mouse
参考价格
6190.47 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Retinal Dehydrogenase 1/ALDH1A1 Antibody, clone 8D7.1
Retinal Dehydrogenase 1, RALDH 1, RalDH1, ALDH-E1, ALHDII, Aldehyde dehydrogenase family 1 member A1, Aldehyde dehydrogenase, cytosolic
产品介绍:

产品说明

一般描述

Retinal dehydrogenase 1 (EC 1.2.1.36; UniProt P00352; also known as Aldehyde dehydrogenase cytosolic, Aldehyde dehydrogenase family 1 member A1, ALDH-E1, ALHDII, RALDH 1, RalDH1) is encoded by the ALDH1A1 (also known as ALDC, ALDH1, PUMB1) gene (Gene ID 216) in human. ALDH1A1, ALDH1A2, and ALDH1A3 constitute the ALDH1A subfamily of aldehyde dehydrogenases that catalyze the oxidation of all-trans retinal and 9-cis retinal to all-trans retinoic acid and 9-cis retinoic acid, respectively. In addition to its role in detoxifing 4-hydroxy-2-nonenal (4-HNE) in the lens and cornea, ALDH1A1 is also involved in many other biological processes, including stem cell maintenance, UV-radiation resistance, melanogenesis, and spermatogenesis, by catalyzing the conversion of specific aldehydes to their corresponding carboxylic acids.

免疫原

GST-tagged recombinant protein corresponding to the N-terminal of human Retinal Dehydrogenase 1/ALDH1A1.
Epitope: N-terminal

应用

This Anti-Retinal Dehydrogenase 1/ALDH1A1 Antibody, clone 8D7.1 is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of Retinal Dehydrogenase 1/ALDH1A1.
Western Blotting Analysis: 1.0 µg/mL from a representative lot detected Retinal Dehydrogenase 1/ALDH1A1 in 10 µg of human cerebellum tissue lysate.
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Retinal Dehydrogenase 1/ALDH1A1 in human testis tissue.
Research Sub Category
Signaling Neuroscience
Research Category
Neuroscience

质量

Evaluated by Western Blotting in HepG2 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Retinal Dehydrogenase 1/ALDH1A1 in 10 µg of HepG2 cell lysate.

目标描述

~55 kDa observed

外形

Format: Purified
Purified mouse monoclonal IgG1k antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆8D7.1, monoclonal
species reactivityhuman
technique(s)immunohistochemistry: suitable (paraffin)
western blot: suitable
同位素/亚型IgG1κ
NCBI登记号NP_000680
UniProt登记号P00352
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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