Anti-RFC5 antibody produced in rabbit

产品说明

免疫原

Synthetic peptide directed towards the N terminal region of human RFC5

应用

Anti-RFC5 antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/ml and for immunohistochemistry at a concentration of 4-8μg/ml.

生化/生理作用

Replication factor C (RFC), also referred to as activator 1, is a protein complex comprising of five distinct subunits of 140, 40, 38, 37, and 36kDa. DNA polymerase delta and epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C for elongation of primed DNA templates. RFC5 gene encodes the 36kDa subunit that forms the core complex along with the 38 and 40kDa subunits. It also interacts with proliferating cell nuclear antigen (PCNA) and preserves modified PCNA from phosphorylation.

序列

Synthetic peptide located within the following region: METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINE

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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