产品说明
一般描述
Receptor interacting serine/threonine kinase 2 (RIPK2) or RICK is a serine/threonine kinase. It contains a kinase domain at the amino-terminal, an intermediate domain and a caspase activation and recruitment domain (CARD) at the carboxy-terminal. The gene encoding RIPK2 is localized on human chromosome 8q21.3.
免疫原
RICK antibody was raised against a peptide corresponding to amino acids near the amino terminus of human RICK.
生化/生理作用
Receptor interacting serine/threonine kinase 2 (RIPK2) or RICK is activated during innate immune responses and acts as a scaffold for downstream effectors. It functions in nuclear factor-κB (NFκB) activation pathways. The protein also has roles in toll-like receptor (TLR)-signaling pathways and in the production of inflammatory cytokines.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
联系
The action of this antibody can be blocked using blocking peptide SBP3500426.
外形
Supplied in PBS with 0.02% sodium azide.
基本信息
| MDL编号 | MFCD02097357 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | predicted mol wt 59 kDa |
| species reactivity | human, mouse, rat |
| technique(s) | immunocytochemistry: suitable immunofluorescence: suitable indirect ELISA: suitable western blot: suitable |
| NCBI登记号 | O43353 |
| UniProt登记号 | O43353 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... RIPK2(8767) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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