产品说明
一般描述
Ribonucleoside-diphosphate reductase subunit M2 (RRM2) is a cytoplasmic protein, which catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates, and plays an important role in DNA damage and repair. RRM2 has been implicated in various types of cancer.
免疫原
GST-tagged recombinant protein corresponding to human RRM2.
应用
Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected RRM2 in HepG2 and A431 cells.
Research Sub Category
Apoptosis - Additional
Detect Ribonucleotide Reductase using this mouse monoclonal antibody, Anti-RRM2 Antibody, clone 4D1.2 validated for use in western blotting & ICC.
Research Category
Apoptosis & Cancer
质量
Evaluated by Western Blotting in HeLa cell lysate.
Western Blotting Analysis: 0.2 µg/mL of this antibody detected RRM2 in 10 µg of HeLa cell lysate.
目标描述
~45 kDa observed
外形
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
HeLa cell lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | 4D1.2, monoclonal |
species reactivity | human |
technique(s) | immunocytochemistry: suitable western blot: suitable |
同位素/亚型 | IgG1κ |
NCBI登记号 | NP_001025 |
UniProt登记号 | P31350 |
运输 | wet ice |
Gene Information | human ... RRM2(6241) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich