产品说明
一般描述
Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak. The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Methyltransferase mediates mRNA cap 2′-O-ribose methylation to the 5′-cap structure of viral mRNAs. N7-methyl guanosine cap is a prerequisite for binding of nsp16. Therefore plays an essential role in viral mRNAs cap methylation which is essential to evade immune system.
免疫原
Anti-SARS-CoV-2 (COVID-19) NSP16 antibody was raised against a peptide corresponding to 16 amino acids near the central domain of SARS-CoV-2 (COVID-19) NSP16 protein. The immunogen is located within 120-170 amino acids of the SARS-CoV-2 (COVID-19) NSP16 protein.
应用
Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) NSP16 antibody can detect 2 ng of free peptide at 1 μg/mL in ELISA. It can detect SARS-CoV-2 NSP16 recombinant protein by ELISA and WB. All other applications and species not yet tested.
外形
Supplied in PBS containing 0.02% sodium azide.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | liquid |
| species reactivity | SARS coronavirus |
| 浓度 | 1 mg/mL |
| technique(s) | ELISA: suitable immunohistochemistry: suitable western blot: suitable |
| 同位素/亚型 | IgG |
| NCBI登记号 | YP_009725311 |
| UniProt登记号 | P0DTC1 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | SARS coronavirus ... ORF1ab(43740578) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
