Anti-Seasonal H1N1 Nonstructural Protein 1 antibody produced in rabbit

产品说明

一般描述

Seasonal H1N1 Nonstructural Protein 1 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from patients in Mexico and the United States. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2′-5′OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the anti-viral protein kinase PKR.

免疫原

NS1 antibody was raised against a synthetic peptide from the seasonal Influenza NS1 protein.The immunogen is located within the last 50 amino acids of Seasonal H1N1 Nonstructural Protein 1.

应用

NS1 antibody can be used for the detection of the NS1 protein from the H1N1 strain of Seasonal Influenza A in ELISA.

外形

Supplied in PBS containing 0.02% sodium azide.

产品性质

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