产品说明
一般描述
Sestrins are stress-inducible proteins. The SESN1 (sestrin 1) gene is located on human chromosome 6q21.
Anti-SESN1 Antibody detects endogenous levels of total SESN1 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human SESN1.
Immunogen Range: 271-320
生化/生理作用
Knockdown of SESN1 (sestrin 1) blocks cell cycle progression. Sestrin 1 acts as an antioxidant and as inhibitor of target of rapamycin complex 1. It is considered as a p53 target gene and it helps to connect between genotoxic stress, p53 and the mTOR signaling pathway.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 56 kDa |
| species reactivity | human, mouse |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:20000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI登记号 | Q9Y6P5 |
| UniProt登记号 | Q9Y6P5 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... SESN1(27244) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
