产品说明
一般描述
Smad1 (SMAD family member 1) is a transcriptional activator, that is located on chromosome 4q31.
免疫原
Peptide sequence around aa. 461-465 (I-S-S-V-S), according to the protein SMAD1.
生化/生理作用
SMAD1 (SMAD family member 1) protein has a major role in disease development, hence it acts as a biologic prognostic factor in diseases. The miR-345 repress the multiplication, invasion and migration of prostate cancer by downregulating Smad1.
特点和优势
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目标描述
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | ~55 kDa |
| species reactivity | rat, human, mouse |
| 浓度 | 1 mg/mL |
| technique(s) | indirect immunofluorescence: 1:100-1:200 western blot: 1:500-1:1000 |
| 同位素/亚型 | IgG |
| 免疫原序列 | (I-S-S-V-S) |
| NCBI登记号 | NP_001003688.1 |
| UniProt登记号 | Q15797 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... SMAD1(4086) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
