产品说明
一般描述
Snail family transcriptional repressor 1 (SNAIL) is a transcription factor and the gene encoding it is localized on human chromosome 20q13.13.
应用
ANTI-SNAIL (N-TERM D24) antibody produced in rabbit has been used in Western Blotting.
生化/生理作用
Snail family transcriptional repressor 1 (SNAIL) acts as a repressor of genes associated with the epithelial phenotype like E-cadherin and increases the expression of genes linked with the mesenchymal phenotype. It has a role in epithelial-mesenchymal transition. The protein aids in G1 transition (early to late) in the cell cycle. SNAIL also modulates cell-matrix adhesion.
外形
Supplied in PBS with 0.09% (W/V) sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | IgG fraction of antiserum |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | 29083 Da |
species reactivity | human |
technique(s) | immunohistochemistry: 1:10-1:50 western blot: 1:1000 |
NCBI登记号 | NP_005976.2 |
UniProt登记号 | O95863 |
application(s) | research pathology |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... SNAI1(6615) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich