产品说明
一般描述
The antibody detects endogenous level of total SPARC protein.
免疫原
Peptide sequence around aa. 52-56 (V-G-E-F-D), according to the protein NP_003109.1
特点和优势
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目标描述
Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca2+ with a low affinity and an EF-hand loop that binds a Ca2+ ion with a high affinity.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | ~42 kDa |
| species reactivity | human |
| 浓度 | 1 mg/mL |
| technique(s) | western blot: 1:500-1:1000 |
| 同位素/亚型 | IgG |
| 免疫原序列 | (V-G-E-F-D) |
| NCBI登记号 | NM_003118.2 |
| UniProt登记号 | P09486 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... SPARC(6678) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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