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Anti-SPRY2 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV50523
规格纯度
affinity isolated antibody
参考价格
6889.23 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-SPRY2 antibody produced in rabbit
Anti-hSPRY2
Anti-MGC23039
Anti-Sprouty homolog 2 (Drosophila)
产品介绍:

产品说明

一般描述

The gene SPRY2 (Sprouty homolog 2) is mapped to human chromosome 13q31.1. SPRY2 localizes in the cytoplasm and co-localizes with microtubules.

免疫原

Synthetic peptide directed towards the N terminal region of human SPRY2

应用

Anti-SPRY2 antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.

生化/生理作用

Sprouty proteins are inhibitors of receptor tyrosine kinase signaling proteins and mediators of organogenesis, branching of lung alveoli and endothelial tubes. They inhibit the activity of Ras/Erk pathway. SPRY2 (Sprouty homolog 2) is bimodal regulator of epidermal growth factor receptor (EGFR)/mitogen-activated protein kinase signaling. SPRY2 is down-regulated in epithelial ovarian cancer. Down-regulation of SPRY2 in high-grade serous ovarian carcinoma promotes EGF-induced E-cadherin levels, thereby resulting in cell invasion.

序列

Synthetic peptide located within the following region: MEARAQSGNGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIR

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 35 kDa
species reactivityrat, mouse, pig, human, dog
浓度0.5 mg - 1 mg/mL
technique(s)immunohistochemistry: suitable
western blot: suitable
NCBI登记号NP_005833
UniProt登记号O43597
运输wet ice
储存温度−20℃
Gene Informationhuman ... SPRY2(10253)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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