Anti-SUMF1 antibody produced in goat

产品说明

一般描述

Sulfatase modifying factor 1 (SUMF1) or formylglycine-generating enzyme (FGE) is a 41kDa glycoprotein. It is localized at the lumen of the endoplasmic reticulum. The protein consists of an amino-terminal domain and a core domain with the active site. The gene encoding SUMF1 is localized on human chromosome 3p26.1 and contains nine exons.

免疫原

Peptide with sequence CETLNPKGPPSGKDR, from the internal region of the protein sequence according to NP_877437.2.

生化/生理作用

Sulfatase modifying factor 1 (SUMF1) converts a highly conserved cysteine in the catalytic domain of sulfatase to form C α-formylglycine (FGly) by post-translational modification. Mutations in the gene encoding this protein have been associated with multiple sulfatase deficiency.

特点和优势

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外形

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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