产品说明
一般描述
Monoclonal Anti-Sumo-2/3 (rat IgG2a isotype) is derived from the hybridoma 3H12 produced by the fusion of mouse myeloma cells and splenocytes from rat immunized with a human SUMO3 fusion protein.
Small ubiquitin-like modifier 3 (SUMO3) is encoded by the gene mapped to human chromosome 21q22.3. The protein belongs to the ubiquitin-like protein family and is expressed mainly in cytoplasm.
免疫原
human SUMO3 fusion protein
应用
Monoclonal Anti-Sumo-2/3 has been used in immunoblotting and immunocytochemistry.
生化/生理作用
Small ubiquitin-like modifier (SUMO) was identified as a post-translational protein modifier.
Small ubiquitin-like modifier 3 (SUMO3) plays a vital role in enhancing cellular responses to environmental stress. It acts as a key element of the leukemogenic network in transient myeloproliferative disorder (TMD) of the newborn/acute megakaryoblastic leukaemia (AMKL).
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD03455941 |
NACRES | NA.41 |
产品性质
偶联物 | unconjugated |
抗体形式 | purified from hybridoma cell culture |
antibody product type | primary antibodies |
克隆 | 3H12, monoclonal |
形式 | buffered aqueous solution |
分子量 | ~11 kDa |
species reactivity | mouse, human, rat |
浓度 | ~1.0 mg/mL |
technique(s) | immunocytochemistry: suitable western blot: 2-4 μg/mL using HeLa cell nuclear extract |
UniProt登记号 | P55854 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... SUMO3(6612) mouse ... Sumo3(20610) rat ... Sumo3(499417) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich