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位置:首页 > 品牌 > Sigma-Aldrich > Anti-Suv4–20h2 Antibody, clone 6B9

Anti-Suv4–20h2 Antibody, clone 6B9

品牌
Sigma-Aldrich
货号
MABE369
规格纯度
clone 6B9, from rat
参考价格
5854.74 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Suv4–20h2 Antibody, clone 6B9
Histone-lysine N-methyltransferase SUV420H2, Lysine N-methyltransferase 5C, Suppressor of variegation 4-20 homolog 2, Su(var)4-20 homolog 2, Suv4-20h2
产品介绍:

产品说明

一般描述

Suppressor of variegation 4-20 homolog 2 (Suv4-20h2), also known as Lysine N-methyltransferase 5C (KMT5C), is a Histone-lysine N-methyltransferase that specifically trimethylates Lys-20 of histone H4. Suv4-20h2 mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. In mammals, Histone H4 Lys-20 trimethylation (H4K20me3) is one of the most common chromatin modifications and it has been implicated in various biological processes, including heterochromatin formation, telomere function, imprinting, X inactivation, DNA damage repair and cancer progression.

免疫原

GST-tagged recombinant protein corresponding to human Suv4-20h2.

应用

Research Category
Epigenetics & Nuclear Function
Research Sub Category
Chromatin Biology
Detect the Suv4–20h2 protein using this Anti-Suv4–20h2, clone 6B9 validated for use in WB.

质量

Evaluated by Western Blot in H9 human embryonic stem cell lysate.

Western Blot Analysis: 4.0 µg/mL of this antibody detected Suv4-20h2 in 10 µg of H9 human embryonic stem cell lysate.

目标描述

~53 kDa observed. Uniprot describes 2 isoforms produced by alternative splicing at ~11 kDa and ~15 kDa

外形

Format: Purified
Purified rat monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
H9 human embryonic stem cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源rat
抗体形式purified antibody
antibody product typeprimary antibodies
克隆6B9, monoclonal
species reactivityhuman
technique(s)western blot: suitable
同位素/亚型IgG2bκ
NCBI登记号NP_116090
UniProt登记号Q86Y97
运输wet ice
Gene Informationhuman ... SUV420H2(84787)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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