产品说明
一般描述
Synaptopodin (SYNPO) is an actin-associated protein that may play an important role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. It is expressed in the cerebral cortex. Mutations in SYNPO may be associated with nephrotic syndrome.
免疫原
Epitope: Near C-terminus.
KLH-conjugated linear peptide corresponding to a sequence near the C-terminus of human SYNPO.
应用
Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected SYNPO in human brain tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
Detect Synaptopodin using this rabbit polyclonal antibody, Anti-Synaptopodin Antibody validated for use in western blotting & IHC.
质量
Evaluated by Western Blotting in rat brain tissue lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected SYNPO in 15 µg of rat brain tissue lysate.
目标描述
~95 kDa observed. Uniprot describes three isoforms at ~74 kDa, ~96 kDa, and ~97 kDa Uncharacterized bands may appear in some lysates.
外形
Affinity purified.
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Rat brain tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human, rat |
technique(s) | immunohistochemistry: suitable western blot: suitable |
UniProt登记号 | Q8N3V7 |
运输 | wet ice |
Gene Information | human ... SYNPO(11346) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich