产品说明
一般描述
The syndecans are transmembrane proteoglycans that place structurally heterogeneous heparan sulfate chains at the cell surface and a highly conserved polypeptide in the cytoplasm. Syntenin (also known as SDCBP) is an approximately 33 kDa scaffolding protein that that binds to kainate receptor subunits via a PDZ interaction. There is extensive colocalization of syntenin and kainate receptors with particularly intense labeling for both proteins at growth cones. It is proposed that syntenin has a role both in controlling membrane organization and in determining the formation and maturation of synapses.
免疫原
GST-tagged recombinant protein corresponding to human Syntenin-1. The immunogen has a 98% homology to Mouse and Rat.
应用
Research Category
Neuroscience
Research Sub Category
Developmental Signaling
Detect Syntenin-1 using this Anti-Syntenin-1 Antibody, clone 4F4.1 validated for use in western blotting.
质量
Evaluated by Western Blotting in HEK293 cell lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected Syntenin-1 in 10 µg of HEK293 cell lysate.
目标描述
~32 kDa observed
外形
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified
Format: Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | 4F4.1, monoclonal |
species reactivity | human |
浓度 | 1 mg/mL |
technique(s) | western blot: suitable |
同位素/亚型 | IgG1κ |
NCBI登记号 | NP_001007068 |
UniProt登记号 | O00560 |
运输 | wet ice |
Gene Information | human ... SDCBP(6386) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich