产品说明
一般描述
The synaptophysin-like protein 1, also known as pantophysin, is a homolog of the neuroendocrine-specific protein synaptophysin, with the highest level of homology across its four transmembrane domains. Unlike synaptophysin however, SYPL1 is ubiquitously expressed and found in small cytoplasmic transport vesicles regardless of their content. SYPL1 is thought to play a multifunctional role in vesicle biogenesis and transport and is a component of adipocyte transport vesicles, and thus may be involved in adipocyte secretion. SYPL1 also interacts with vesicle-associated membrane protein 2 (VAMP-2) in adipocytes and associates with GLUT4-containing vesicles.
免疫原
KLH-conjugated linear peptide corresponding to human SYPL1.
应用
Anti-SYPL1 Antibody is a highly specific rabbit polyclonal antibody, that targets Synaptophysin-like protein 1 & has been tested in western blotting & IHC.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected SYPL1 in human cerebellum, colon, and thalamus tissues.
质量
Evaluated by Western Blotting/Peptide Inhibition Assay in human brain tissue lysate.
Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected SYPL1 in 15 µg of human brain tissue lysate.
目标描述
~28 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 2 isoforms at ~26 kDa and ~29 kDa
外形
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Human brain tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human |
technique(s) | immunohistochemistry: suitable western blot: suitable |
UniProt登记号 | Q16563 |
运输 | wet ice |
Gene Information | human ... SYPL1(6856) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich