产品说明
一般描述
Anti-TAK1 antibody detects endogenous levels of total TAK1 protein.
The TAK1 (Transforming growth factor β activated kinase 1) gene is mapped to human chromosome 6q15. It encodes for a mitogen-activated protein kinase 7 containing serine-threonine/tyrosine-protein kinase catalytic domain and a coiled-coil domain at the C-terminal.
免疫原
The antiserum was produced against synthesized peptide derived from human TAK1.
Immunogen Range: 161-210
生化/生理作用
TAK1 (Transforming growth factor β (TGF-β) activated kinase 1) is activated by TGF-β and other inflammatory stimuli such as chemical and physical agents causing stress, cytokines, and microorganism moieties. TAK1 participates in mitogen-activated protein kinase (MAPK)-p38 signaling pathway. TAK1 is involved in the regulation of osteogenesis. TAK1 is important for productive autophagy.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD02097469 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 67 kDa |
| species reactivity | rat, mouse, human |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:1000 western blot: 1:500-1:1000 |
| NCBI登记号 | O43318 |
| UniProt登记号 | O43318 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... MAP3K7(6885) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
