产品说明
一般描述
Tensin 1, also known as TNS1, is a member of tensin protein family. Tensins are multi domain proteins containing homologous C1, protein phosphatases (PTPases), C2, Src homology 2 (SH2) domains and pTyr-binding (PTB) domains. Tensin 1 mRNA is widely expressed in mouse embryo and various human adult tissues and is localized to focal adhesions.
免疫原
synthetic peptide corresponding to a sequence located in the internal region of human tensin1, conjugated to KLH. The corresponding sequence is identical in rat and mouse tensin1.
应用
Anti-Tensin 1 (internal) antibody produced in rabbit has been used in immunoblotting.
生化/生理作用
Tensins play an important role in regulating cell shape and motility. Tensin 1 is involved in organizing the actin cytoskeleton and mediating signal transduction. TNS1 is implicated in myofibroblast differentiation. In addition, it also helps myofibroblasts to form nascent fibronectin and collagen matrix.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 225 kDa (rat) antigen ~150 kDa (human) |
| species reactivity | human, rat |
| 增强验证 | recombinant expression Learn more about Antibody Enhanced Validation |
| 浓度 | ~1.5 mg/mL |
| technique(s) | western blot: 1-2 μg/mL using HEK-293T cells overexpressing human tensin1. western blot: 1.5-3 μg/mL using lysates of A10 cells |
| UniProt登记号 | Q9HBL0 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... TNS1(7145) mouse ... Tns1(21961) rat ... Tns1(301509) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
