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Anti-TIM-1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB3500252
规格纯度
affinity isolated antibody, buffered aqueous solution
参考价格
5045.46 *本价格含增值税费
促销
服务
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  • 增值税票
数量
-+
产品名称:
Anti-TIM-1 antibody produced in rabbit
Anti-T cell immunoglobulin and mucin domain containing protein 1
产品介绍:

产品说明

一般描述

Hepatitis A virus cellular receptor 1 (HAVCR1) or T-cell immunoglobulin and mucin protein (TIM-1) is a type 1 transmembrane glycoprotein. The protein is found in the apical membrane of cells. It is expressed in the kidney, testis and activated CD4+ T-cells. It possesses a six-cysteine immunoglobulin-like domain, a T/SP rich domain and two N-glycosylation sites. The TIM-1 gene is localized on human chromosome 5q33.2.

免疫原

TIM-1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human TIM-1.

应用

Anti-TIM-1 antibody produced in rabbit has been used in immunofluorescence.

生化/生理作用

Hepatitis A virus cellular receptor 1 (HAVCR1) regulates susceptibility to human immunodeficiency virus-1 (HIV-1) infection. It is upregulated in injured kidneys. HAVCR1 inhibits the activation of the Ga12 G-protein by blocking its association to GTP. Polymorphisms in the protein have been associated with immune dysfunction.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

联系

The action of this antibody can be blocked using blocking peptide SBP3500252.

外形

Supplied in PBS with 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量predicted mol wt 40 kDa
species reactivityhuman, mouse
technique(s)immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
NCBI登记号NP_036338
UniProt登记号Q96D42
运输dry ice
储存温度−20℃
Gene Informationhuman ... HAVCR1(26762)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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