产品说明
一般描述
The Tom (translocase of the mitochondrial outer membrane) complex consists of two integral membrane import receptors, Tom20 and Tom70 (translocase of outer mitochondrial membrane 70) and a GIP (general import pore) complex. TOM70/ TOMM70A has 12 coding exons and spans about 37kb. It is abundantly expressed in human tissues and is located on human chromosome 3q13.1-q13.2. It belongs to the tetratricopeptide repeat (TPR) co-chaperone family. TOM70 has a dicarboxylate TPR clamp domain that can interact with molecular chaperones like Hsp70 (heat shock protein 70)/Hsc70 and/or Hsp90.
免疫原
TOM70 antibody was raised against a 17 amino acid peptide near the amino terminus of human TOM70.
生化/生理作用
TOM70/ TOMM70A (translocase of outer mitochondrial membrane 70) has the capability to identify preproteins with internal hydrophobic targeting sequences. It contributes in the transportation of several large hydrophobic matrix proteins. The import receptor Tom70 acts as a docking site for cytosolic multichaperone complexes.
特点和优势
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联系
The action of this antibody can be blocked using blocking peptide SBP3500459.
外形
Supplied in PBS with 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | predicted mol wt 67 kDa |
| species reactivity | mouse, rat, human |
| technique(s) | immunofluorescence: suitable immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
| NCBI登记号 | NP_055635 |
| UniProt登记号 | O94826 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... TOMM70A(9868) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
