产品说明
一般描述
TorsinA can regulate the cellular trafficking of the dopamine transporter, as well as other polytopic membrane-bound proteins, including G protein-coupled receptors, transporters, and ion channels. TorsinA is found in the dopamine neurons that are lost in PD, and is a component of Lewy bodies. in addition, a genetic defect in TorsinA underlies Torsion dystonia, a disease characterized by painful muscle contractions that result in uncontrollable distortions.
特异性
TorsinA
免疫原
Maltose binding protein fusion protein from human torsinA.
应用
Research Sub Category
Developmental Neuroscience
Neurodegenerative Diseases
Research Category
Neuroscience
This Anti-TorsinA Antibody is validated for use in IP, WB, IC for the detection of TorsinA.
目标描述
37kDa
外形
Ascites
Liquid. Contaings no preservative
储存及稳定性
Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.
分析说明
Control
Positive Control: Human brain lysate, NGF treated PC12 cells.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | ascites fluid |
antibody product type | primary antibodies |
克隆 | monoclonal |
species reactivity | human, mouse, rat |
manufacturer/tradename | Chemicon® |
technique(s) | immunocytochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
同位素/亚型 | IgG1 |
NCBI登记号 | NM_000113.2 |
UniProt登记号 | O14656 |
运输 | dry ice |
Gene Information | human ... TOR1B(27348) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich