产品说明
一般描述
Tumor associated calcium signal transducer 2 (TACSTD2), also known as trophoblast cell surface antigen 2 (TROP2), is a 36 kDa protein and part of the TACSTD family. The gene encoding this cell surface glycoprotein is localized on human chromosome 1p32.1.
免疫原
Peptide with sequence C-HYEQPTIQIELRQN from the internal region of the protein sequence according to NP_002344.2.
生化/生理作用
Trophoblast cell surface antigen 2 (TROP2) has a role in epithelial-mesenchymal transition. It modulates stem cell activity and is crucial in promoting cell self-renewal and survival. TROP2 increases intracellular calcium levels. The protein is overexpressed in many cancers. It has been shown to influence the proliferation and migration of gallbladder cancer cells.
特点和优势
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外形
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
基本信息
| MDL编号 | MFCD03456064 |
产品性质
| 质量水平 | 100 |
| 生物来源 | goat |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | ELISA: suitable western blot: suitable |
| UniProt登记号 | P09758 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... TACSTD2(4070) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 |
| 预防措施声明 | P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 |
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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