产品说明
一般描述
Anti-ULK3 is produced in rabbit using as the immunogen a synthetic peptide corresponding to a fragment of human ULK3, conjugated to KLH. Unc-51-like kinase 3 (ULK3) belongs to the ULK family of serine/threonine kinases. ULK3 is an autophagy related protein with an N-terminal kinase domain, which shows high similarity to those of ULK1 and ULK2. ULK3 localizes to the elongating isolation membrane upon autophagy activation.
应用
Anti-ULK3 antibody produced in rabbit has been used in immunoblotting.
生化/生理作用
Unc-51-like kinase 3 (ULK3) controls abscission timing in response to lagging chromosomes. Overexpression of ULK3 induces autophagy and senescence. ULK3 is also a positive regulator of the Hedgehog signalling pathway.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.44 |
产品性质
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~50 kDa |
| species reactivity | human |
| 包装 | antibody small pack of 25 μL |
| 浓度 | ~1 mg/mL |
| technique(s) | western blot: 1-2 μg/mL using whole extracts of human U87 cells |
| UniProt登记号 | Q6PHR2 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ULK3(25989) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
