您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 品牌 > Sigma-Aldrich > Anti-WDR5 Antibody, clone 7B11

Anti-WDR5 Antibody, clone 7B11

品牌
Sigma-Aldrich
货号
MABE428
规格纯度
ascites fluid, clone 7B11, from mouse
参考价格
5180.56 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-WDR5 Antibody, clone 7B11
WD repeat-containing protein 5, BMP2-induced 3-kb gene protein
产品介绍:

产品说明

一般描述

WD repeat-containing protein 5 (WDR5) or alternatively BMP2-induced 3kb gene protein, is encoded by the human gene named WDR5/BIG3 and is part of a family of WD-40 repeat proteins that appear to facilitate the formation of multi-protein complexes much like a sticky tape will bind a variety of components together. The WD repeat proteins are involved in a wide array of cellular functions and processes including cell cycle progression, homeobox gene activation, apoptosis, gene regulation and histone methylation. One of WDR5 best studied activities is as part of a multi-protein complex that facilitates the methylation of histones, particularly histone H3, through its interaction with MLL a histone methyltransferase. WDR5 is also expressed in developing bone cells including osteoblasts, chondrocytes, and marrow stromal cells and works to accelerate osteoblast differentiation and positively promotes Wnt signaling in developing bone tissues. EMD-Millipore’s Anti-WDR5 mouse monoclonal antibody has been tested in western blot using HeLa cell lysates.

免疫原

Purified recombinant fragment of human WDR5 expressed in E. Coli.

应用

Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Anti-WDR5 Antibody, clone 7B11 is a highly specific mouse monoclonal antibody & that targets WDR5 & has been tested in western blotting.

质量

Evaluated by Western Blotting in HeLa cell lysate.

Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected WDR5 in HeLa cell lysate.

Optimal working dilutions must be determined by end user.

目标描述

~40 kDa observed

外形

Mouse monoclonal IgG2b ascitic fluid containing up to 0.1% sodium azide.
Unpurified

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析说明

Control
HeLa cell lysate

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式ascites fluid
antibody product typeprimary antibodies
克隆7B11, monoclonal
species reactivityhuman
technique(s)western blot: suitable
同位素/亚型IgG2b
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品