产品说明
一般描述
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 543-732 of human XRCC5 (NP_066964.1).
外形
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存及稳定性
Store at -20℃. Avoid freeze / thaw cycles.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 82 |
| species reactivity | rat, mouse, human |
| 浓度 | 0.63 mg/ml |
| technique(s) | immunofluorescence: 1:20-1:100 immunohistochemistry: 1:100-1:200 immunoprecipitation (IP): 1:50-1:200 western blot: 1:500-1:2000 |
| UniProt登记号 | P13010 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... XRCC5(7520) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
