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Anti-ZIP14 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB3500603
规格纯度
affinity isolated antibody, buffered aqueous solution
参考价格
6662.67 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-ZIP14 antibody produced in rabbit
Anti-NET34
Anti-Slc39A14
Anti-LZT-Hs4
Anti-Solute carrier family 39 member A14
产品介绍:

产品说明

一般描述

Solute carrier family 39 member 14 or Zrt- and Irt-like protein 14 (ZIP14), a transmembrane metal ion transporter, is a member of the LIV-1 subfamily. It contains eight transmembrane domains (TMDs), a metalloprotease, and a histidine-rich motif. ZIP14 is majorly expressed in the pancreas, liver, and heart. The ZIP14 gene is mapped to human chromosome 8p21.3.

免疫原

ZIP14 antibody was raised against a 16 amino acid peptide near the center of human ZIP14.

应用

Anti-ZIP14 antibody produced in rabbit has been used in immunoblotting. 1:2500

生化/生理作用

Zrt- and Irt-like protein 14 (ZIP14) is a divalent metal transporter specific for zinc (Zn). However, some studies report, it also mediates the transport of manganese (Mn), iron (Fe), and cadmium (Cd). ZIP14 along with ZIP8 are prime Mn2+ importers of the brain′s capillary bed and in human brain microvascular endothelial cells (HBMVEC) in in vitro conditions. Mutations in the ZIP14 gene lead to manganese dyshomeostasis, which in turn results in manganese accumulation in childhood-onset parkinsonism–dystonia patients.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

联系

The action of this antibody can be blocked using blocking peptide SBP3500603.

外形

Supplied in PBS with 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量predicted mol wt 54 kDa
species reactivityhuman, mouse, rat
technique(s)ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable
NCBI登记号NP_001128625
UniProt登记号Q15043
运输dry ice
储存温度−20℃
Gene Informationhuman ... SLC39A14(23516)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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