ANTI-ZKSCAN3 antibody produced in mouse

产品说明

一般描述

Zinc finger with KRAB and SCAN domains 3 (ZKSCAN3) is encoded by the gene mapped to human chromosome 6p22.1. The encoded protein belongs to the zinc finger family of DNA-binding proteins.

免疫原

ZKSCAN3 (NP_077819.1, 1 a.a. ~ 538 a.a) full-length human protein.

Sequence
MARELSESTALDAQSTEDQMELLVIKVEEEEAGFPSSPDLGSEGSRERFRGFRYPEAAGPREALSRLRELCRQWLQPEMHSKEQILELLVLEQFLTILPGNLQSWVREQHPESGEEVVVLLEYLERQLDEPAPQVSGVDQGQELLCCKMALLTPAPGSQSSQFQLMKALLKHESVGSQPLQDRVLQVPMLAHGGCCREDAVVASRLTPESQGLLKVEDVALTLTPEWTQQDSSQGNLCRDEKQENHGSLVSLGDEKQTKSRDLPPAEELPEKEHGKISCHLREDIAQIPTCAEAGEQEGRLQRKQKNATGGRRHICHECGKSFAQSSGLSKHRRIHTGEKPYECEECGKAFIGSSALVIHQRVHTGEKPYECEECGKAFSHSSDLIKHQRTHTGEKPYECDDCGKTFSQSCSLLEHHRIHTGEKPYQCSMCGKAFRRSSHLLRHQRIHTGDKNVQEPEQGEAWKSRMESQLENVETPMSYKCNECERSFTQNTGLIEHQKIHTGEKPYQCNACGKGFTRISYLVQHQRSHVGKNILSQ

生化/生理作用

Zinc finger with KRAB and SCAN domains 3 (ZKSCAN3) acts as a zinc finger transcription factor and plays an essential role in stimulating prostate cancer cell migration. Elevated expression of the gene is associated with various types of cancers, including prostate cancer, colon tumors, colorectal cancer (CRC) and multiple myeloma (MM). The encoded protein functions as a chief transcriptional repressor of autophagy.

外形

Solution in phosphate buffered saline, pH 7.4

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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