产品说明
一般描述
Zinc finger protein 207 (ZNF207) consists of a N-terminal zinc finger domain and a conserved GLE-2-binding sequence (GLEBS) motif, which helps BUB3 (budding uninhibited by benzimidazoles 3) binding. The gene is located on human chromosome 17q11.2.
免疫原
ZNF207 (NP_003448, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKETIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQ
生化/生理作用
Zinc finger protein 207 (ZNF207) maintains BUB3 (budding uninhibited by benzimidazoles 3) protein stability and chromosome congression. This protein interacts with microtubules and maintains chromosome alignment. It also helps in the loading of Bub3 protein to the kinetochores. ZNF207 is essential for maintaining the viability of glioblastoma stem cells.
外形
Solution in phosphate buffered saline, pH 7.4
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 8G7, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 37.84 kDa |
| species reactivity | human |
| technique(s) | indirect ELISA: suitable indirect immunofluorescence: suitable western blot: 1-5 μg/mL |
| 同位素/亚型 | IgG2aκ |
| NCBI登记号 | NM_003457 |
| UniProt登记号 | O43670 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ZNF207(7756) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
