[R-(R*, R*)]-2-(4-Fluorophenyl)-β, δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1Hpyrrole-1-heptanoic acid, calcium salt (2:1) trihydrate

品牌

Sigma-Aldrich

CAS

344423-98-9

货号

SML3030

包装型号

规格纯度

≥98% (HPLC)

参考价格

1053.02 元 *本价格含增值税费

促销

数量

产品名称：

344423-98-9
Atorvastatin Calcium Salt Trihydrate
[R-(R*, R*)]-2-(4-Fluorophenyl)-β, δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1Hpyrrole-1-heptanoic acid, calcium salt (2:1) trihydrate
(betaR,deltaR)-2-(p-Fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoate, calcium salt (2:1) trihyddrate

产品介绍：

产品说明

生化/生理作用

Atorvastatin calcium salt trihydrate is a specific inhibitor of β-Hydroxy β-methylglutaryl-CoA (HMG-CoA) reductase. HMG-CoA reductase is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis. Atorvastatin is used in the treatment of hypercholesterolemia.

基本信息

经验(实验)分子式	C₆₆H₆₈F₂N₄O₁₀ · Ca · 3H₂O
分子量	1209.39

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
旋光性	[α]/D -9.0 to -5.0°, c = 0.5 in DMSO
储存条件	protect from light
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	room temp
SMILES string	O=C(C1=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(C2=CC=C(C=C2)F)=C1C3=CC=CC=C3)NC4=CC=CC=C4.[Ca+2].[3.0H2O]

安全信息

象形图
警示用语：	Danger
危险声明	H351 - H360D
预防措施声明	P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类	Carc. 2 - Repr. 1B
储存分类代码	6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable