产品说明
应用
AUDA may be used in soluble epoxide hydrolase-mediated cell signaling studies.
AUDA has been used in the inhibition of epoxide hydrolase in human macrophages and in inhibition of tumor necrosis factor α (TNF-α)- induced phosphorylation in human aortic smooth muscle cells.
包装
10, 50 mg in glass bottle
生化/生理作用
Inhibition of soluble epoxide hydrolase by AUDA inhibits the metabolism of epoxyeicosatrienoic acids (EETs) and protects end-organs against the damaging effects of salt-sensitive hypertension. AUDA also renders protection against myocardial ischemia-reperfusion injury and cerebral ischemia.
AUDA is a potent inhibitor of soluble epoxide hydrolase
基本信息
| 经验(实验)分子式 | C23H40N2O3 |
| 分子量 | 392.58 |
| MDL编号 | MFCD12912267 |
| PubChem化学物质编号 | 329825206 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: ≥10 mg/mL at warmed to 60 ℃ |
| 储存温度 | −20℃ |
| SMILES string | OC(=O)CCCCCCCCCCCNC(=O)NC12C[C@@H]3C[C@@H](C[C@@H](C3)C1)C2 |
| InChI | 1S/C23H40N2O3/c26-21(27)10-8-6-4-2-1-3-5-7-9-11-24-22(28)25-23-15-18-12-19(16-23)14-20(13-18)17-23/h18-20H,1-17H2,(H,26,27)(H2,24,25,28)/t18-,19+,20-,23- |
| InChI key | XLGSEOAVLVTJDH-UKBVAGSOSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
