Azoramide

产品名称：

932986-18-0
Azoramide
N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]-butanamide
N-{2-[2-(4-Chlorophenyl)-1,3-thiazol-4-yl]ethyl} butanamide

产品介绍：

产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It has dual activity: Azoramide improves endoplasmic reticulum (ER) protein-folding ability and stimulates the expression of ER chaperones that protect cells against ER stress. Azoramide was shown to protect cells from death and dysfunction in multiple models of ER stress. It showed antidiabetic activity in two independent mouse models of obesity by improving insulin sensitivity and protecting pancreatic β cell function against ER stress.

基本信息

经验(实验)分子式	C₁₅H₁₇ClN₂OS
分子量	308.83
MDL编号	MFCD08009374
PubChem化学物质编号	329825964

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 30 mg/mL, clear
储存温度	2-8℃
SMILES string	ClC1=CC=C(C2=NC(CCNC(CCC)=O)=CS2)C=C1
InChI	1S/C15H17ClN2OS/c1-2-3-14(19)17-9-8-13-10-20-15(18-13)11-4-6-12(16)7-5-11/h4-7,10H,2-3,8-9H2,1H3,(H,17,19)
InChI key	VYBFWKKCWTXCQX-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable